The southern region links colonial Arequipa (approx. 2,400m) to the Andean highlands. Above the city rise volcanoes Misti, Chachani, and Pichu Pichu. Roughly 160 km northwest, Colca Canyon offers Inca terraces and the Cruz del Cóndor viewpoint for observing Andean condors. Arequipa is a common stopover for the Puno and Cusco highlands.

The Colca Canyon is located approximately 160 kilometers northwest of Arequipa and is one of the deepest canyons in the world. Along the valley, villages still cultivate ancient agricultural terraces, some of which date back to pre-Incan times. At the Cruz del Cóndor viewpoint, where the canyon floor lies approximately 1,200 meters deeper, Andean condors circle, best observed in the morning.The starting point is the town of Chivay, about a four-hour drive from Arequipa, with thermal baths in the surrounding area.To visit the viewpoints, you need the Colca Tourist Ticket, which you can purchase in Chivay or at the checkpoints.The road leads over high altitudes; plan for acclimatization.

In the Altiplano on the border with Bolivia lies Lake Titicaca at an altitude of approximately 3,810 meters, the highest navigable lake in the world. The city of Puno on the west shore is the starting point for boat tours to the floating reed islands of the Uros and to Taquile Island, whose textile art UNESCO has recognized as intangible cultural heritage. In February, Puno celebrates the Fiesta de la Candelaria, also a UNESCO cultural heritage. The region is accessible by flight to Juliaca, by bus, or by train from Cusco.

Puno is located at about 3,800 meters on the western shore of Lake Titicaca and is the starting point for boat trips on the lake. The city calls itself the “Folklore Capital of Peru”: Every February, it celebrates the Fiesta de la Virgen de la Candelaria with thousands of dancers and musicians, an intangible UNESCO cultural heritage since 2014.On the Plaza de Armas stands the baroque cathedral, completed in 1757. From the hill with the monument to Manco Cápac, the legendary first Inca, you overlook the city and the lake. About 30 kilometers outside, on Lago Umayo, are the funerary towers of Sillustani, built by the Colla before Inca rule.The nearest airport is Inca Manco Cápac Airport in Juliaca. You can also reach Puno by bus or with the PeruRail Titicaca train from Cusco.After arrival, allow yourself time to acclimatize before going on excursions.

Lake Titicaca lies at an altitude of approximately 3,810 meters in the Altiplano and is shared by Peru and Bolivia. It is considered the world's highest navigable lake. From Puno, boats depart for the Uros, islands that the inhabitants build and constantly renew from layers of totora reeds. Their boats are also made from the same reeds.Further out lies the natural island of Taquile, whose inhabitants speak Quechua and are renowned for their woven and knitted textiles. UNESCO recognizes Taquile's textile art as intangible cultural heritage. On the neighboring island of Amantaní, you can stay with families.Day trips to Uros and Taquile start in the morning from Puno's harbor.On the water, it is sunny and windy; bring warm clothing and sun protection.